UGT2B28

Across TCGA cell cohorts, UGT2B28 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UGT2B28-associated genes across cancer lineages are PNLIP, OR2T35, and TPRX1. Each is linked with UGT2B28 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B28-to-partner and partner-to-UGT2B28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PNLIP grouped by UGT2B28-low versus UGT2B28-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B28→partner) and Y-score (partner→UGT2B28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PNLIP →	+0.046	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR2T35 →	+0.086	+4.807	<.001	.006	3	1
BLOOD_Myeloma	TPRX1 →	+0.006	+4.807	<.001	.006	3	1
BLOOD_Myeloma	OR2A5 →	+0.040	+4.807	<.001	.006	3	1
BLOOD_Myeloma	H3C11 →	+0.416	+4.807	<.001	.006	3	1
SKIN	PRG3 →	+0.020	+4.437	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

PNLIP by UGT2B28 expression — BLOOD_Myeloma

Explore this box plot interactively →