Across TCGA pan-cancer cohorts, UGT2B17 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated UGT2B17 data layer compared with 18 for mass-spec protein and 7 for mutation status.
The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UGT2B17 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated UGT2B17 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.
PDAC are the cancer types where UGT2B17 mass-spec protein most reproducibly stratifies survival.