UGT2B17

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UGT2B17 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B17-associated genes across cancer lineages are FoxM1, PDCD4, and PKC-delta_pS664. Each is linked with UGT2B17 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B17-to-partner and partner-to-UGT2B17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B17→partner) and Y-score (partner→UGT2B17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECFoxM1 →+0.314+2.222.004.01132
UCECPDCD4 →-0.605-2.999.002.03532
UCECPKC-delta_pS664 →-0.119-2.999.019.03532
UCECAnnexin-1 →+0.718+3.341.001.00532
UCECeIF4E →+0.197+2.906.027.00131
UCECFOXO3a_pS318_S321 →-0.148-2.584.005.01031
Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

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