Across TCGA cell cohorts, UGT2B17 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible UGT2B17-associated genes across cancer lineages are CCDC172, RBMY1F, and OR2T1. Each is linked with UGT2B17 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B17-to-partner and partner-to-UGT2B17 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B17→partner) and Y-score (partner→UGT2B17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CCDC172 →	+0.006	+5.415	<.001	.004	3	1
SKIN	RBMY1F →	+0.086	+6.022	<.001	.001	3	1
SKIN	OR2T1 →	+0.013	+6.022	<.001	.001	3	1
SKIN	OR11H2 →	+0.030	+4.977	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

UGT2B17 survival (RNA) · tumor vs normal (RNA) · all UGT2B17 data types