Across TCGA patient cohorts, UGT2B15 mutation is significantly associated with the RNA expression of many other genes, with 1,545 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B15-associated genes across cancer lineages are NCAPH2, RNA5SP411, and RNA5SP419. Each is linked with UGT2B15 in more than 2 cancer types. Because this analysis shows association rather than direction, both UGT2B15-to-partner and partner-to-UGT2B15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B15→partner) and Y-score (partner→UGT2B15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCAPH2 →	+0.466	+2.263	<.001	<.001	3	3
UCEC	RNA5SP411 →	+0.662	+1.683	.004	.002	3	3
LUSC	RNA5SP419 →	+0.444	+4.295	<.001	.006	3	3
UCEC	RNA5SP413 →	+0.825	+1.774	<.001	.001	3	3
UCEC	RNA5SP417 →	+0.326	+1.959	.002	.002	3	3
UCEC	RNA5SP422 →	+0.527	+1.745	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,545 associations by consensus.

Exploration

UGT2B15 survival (RNA) · tumor vs normal (RNA) · all UGT2B15 data types