Across TCGA cell cohorts, UGT2B15 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. CNS shows the largest number of these associations.

The most reproducible UGT2B15-associated genes across cancer lineages are RHO, KRTAP4-4, and TAS1R2. Each is linked with UGT2B15 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT2B15-to-partner and partner-to-UGT2B15 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B15→partner) and Y-score (partner→UGT2B15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	RHO →	+0.024	+4.247	.001	.006	3	1
CNS	KRTAP4-4 →	+0.013	+4.169	<.001	.008	3	1
CNS	TAS1R2 →	+0.014	+3.643	<.001	.007	3	1
CNS	TEX33 →	+0.012	+4.772	<.001	.002	3	1
CNS	KRTAP29-1 →	+0.075	+3.643	<.001	.007	3	1
CNS	RNF212B →	+0.152	+3.978	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

Exploration

UGT2B15 survival (RNA) · tumor vs normal (RNA) · all UGT2B15 data types