UGT2B10

Across TCGA patient cohorts, UGT2B10 mutation is significantly associated with the RNA expression of many other genes, with 2,055 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGT2B10-associated genes across cancer lineages are BAP1, RASGRP3-AS1, and RNA5SP413. Each is linked with UGT2B10 in more than 2 cancer types. Because this analysis shows association rather than direction, both UGT2B10-to-partner and partner-to-UGT2B10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BAP1 grouped by UGT2B10-low versus UGT2B10-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2B10→partner) and Y-score (partner→UGT2B10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BAP1 →	+0.296	+2.025	.001	.001	3	3
UCEC	RASGRP3-AS1 →	+0.350	+3.111	.008	<.001	3	3
UCEC	RNA5SP413 →	+0.843	+1.488	<.001	.009	3	3
UCEC	CRYBB2P1 →	+0.463	+2.329	<.001	<.001	3	3
UCEC	L3MBTL2 →	+0.353	+3.185	<.001	<.001	3	3
BLCA	LINC02229 →	+0.217	+5.064	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,055 associations by consensus.

BAP1 by UGT2B10 expression — SKCM

Explore this box plot interactively →