UGT2A2

Across TCGA patient cohorts, UGT2A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,549 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UGT2A2-associated GO terms across cancer lineages are rRNA methylation, Regulation of mRNA processing, and Epithelial tube formation. Each is linked with UGT2A2 in more than 6 cancer types. Because this analysis shows association rather than direction, both UGT2A2-to-partner and partner-to-UGT2A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, rRNA methylation grouped by UGT2A2-low versus UGT2A2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2A2→partner) and Y-score (partner→UGT2A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	rRNA methylation →	+0.075	+0.015	<.001	<.001	3	7
ESCA	Regulation of mRNA processing →	+0.100	+0.029	<.001	<.001	3	7
ESCA	Epithelial tube formation →	+0.068	+0.034	<.001	<.001	3	6
STAD	Positive regulation of cell cycle process →	+0.087	+0.010	<.001	<.001	3	6
ESCA	Positive regulation of telomere maintenance →	+0.092	+0.047	<.001	<.001	3	6
STAD	Maintenance of cell number →	+0.080	+0.013	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,549 associations by consensus.

rRNA methylation by UGT2A2 expression — STAD

Explore this box plot interactively →