UGT2A1

Across TCGA patient cohorts, UGT2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,190 significant associations in total. STAD shows the largest number of these associations.

The most reproducible UGT2A1-associated GO terms across cancer lineages are ATP biosynthetic process, Mitochondrial gene expression, and Nucleoside phosphate biosynthetic process. Each is linked with UGT2A1 in more than 10 cancer types. Because this analysis shows association rather than direction, both UGT2A1-to-partner and partner-to-UGT2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP biosynthetic process grouped by UGT2A1-low versus UGT2A1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2A1→partner) and Y-score (partner→UGT2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	ATP biosynthetic process →	+0.062	+0.082	<.001	<.001	3	10
STAD	Mitochondrial gene expression →	+0.068	+0.113	<.001	<.001	3	10
STAD	Nucleoside phosphate biosynthetic process →	+0.084	+0.139	<.001	<.001	3	10
ESCA	Telomere organization →	+0.063	+0.231	.002	<.001	3	10
ESCA	Positive regulation of telomerase activity →	+0.073	+0.214	<.001	<.001	2	11
ESCA	Morphogenesis of embryonic epithelium →	+0.056	+0.148	<.001	.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,190 associations by consensus.

ATP biosynthetic process by UGT2A1 expression — STAD

Explore this box plot interactively →