UGT2A1

Across TCGA cell cohorts, UGT2A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 396 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UGT2A1-associated GO terms across cancer lineages are Somatic recombination of immunoglobulin genes involved in immune response, Isotype switching, and CD4-positive, alpha-beta T cell activation. Each is linked with UGT2A1 in more than 3 cancer types. Because this analysis shows association rather than direction, both UGT2A1-to-partner and partner-to-UGT2A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Somatic recombination of immunoglobulin genes involved in immune response grouped by UGT2A1-low versus UGT2A1-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT2A1→partner) and Y-score (partner→UGT2A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Somatic recombination of immunoglobulin genes involved in immune response →	+0.057	+0.040	.006	.008	3	4
STOMACH	Isotype switching →	+0.057	+0.040	.006	.008	3	4
SOFT_TISSUE	CD4-positive, alpha-beta T cell activation →	-0.071	-0.027	.001	.005	3	3
SOFT_TISSUE	Skeletal muscle tissue regeneration →	+0.085	+0.030	<.001	.003	3	3
SOFT_TISSUE	Negative regulation of alpha-beta T cell proliferation →	-0.149	-0.031	<.001	.006	3	3
SOFT_TISSUE	Negative regulation of T cell activation →	-0.067	-0.030	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 396 associations by consensus.

Somatic recombination of immunoglobulin genes involved in immune response by UGT2A1 expression — STOMACH

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