UGT1A9

Across TCGA cell cohorts, UGT1A9 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible UGT1A9-associated genes across cancer lineages are PRM2, DEFB108B, and SHISA6. Each is linked with UGT1A9 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT1A9-to-partner and partner-to-UGT1A9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRM2 grouped by UGT1A9-low versus UGT1A9-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT1A9→partner) and Y-score (partner→UGT1A9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	PRM2 →	+0.128	+5.000	<.001	.006	3	1
PANCREAS	DEFB108B →	+0.032	+5.000	<.001	.006	3	1
PANCREAS	SHISA6 →	+0.018	+5.000	.004	.006	3	1
PANCREAS	GPX5 →	+0.022	+5.000	<.001	.006	3	1
OVARY	RXFP2 →	+0.256	+4.228	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PRM2 by UGT1A9 expression — PANCREAS

Explore this box plot interactively →