Across TCGA patient cohorts, UGT1A8 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,929 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UGT1A8-associated GO terms across cancer lineages are Flavonoid glucuronidation, Flavone metabolic process, and Xenobiotic glucuronidation. Each is linked with UGT1A8 in more than 17 cancer types. Because this analysis shows association rather than direction, both UGT1A8-to-partner and partner-to-UGT1A8 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT1A8→partner) and Y-score (partner→UGT1A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	Flavonoid glucuronidation →	+1.255	+3.188	<.001	.007	1	18
CHOL	Flavone metabolic process →	+1.378	+3.282	<.001	.005	2	14
HNSC	Xenobiotic glucuronidation →	+1.111	+0.765	<.001	<.001	3	11
ESCA	NADH oxidation →	+0.085	+0.588	<.001	<.001	3	10
STAD	Primary alcohol metabolic process →	+0.036	+0.236	<.001	<.001	3	10
STAD	Olefinic compound metabolic process →	+0.052	+0.340	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,929 associations by consensus.

Exploration

UGT1A8 survival (RNA) · tumor vs normal (RNA) · all UGT1A8 data types