UGT1A8

Across TCGA patient cohorts, UGT1A8 protein abundance is significantly associated with the protein abundance of many other proteins, with 368 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UGT1A8-associated proteins across cancer lineages are ATF7IP_S57, AZI2_S353, and CAVIN4_S258. Each is linked with UGT1A8 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT1A8-to-partner and partner-to-UGT1A8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UGT1A8 versus ATF7IP_S57 in HNSC, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT1A8→partner) and Y-score (partner→UGT1A8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ATF7IP_S57 →	+2.271	+2.323	<.001	.001	3	1
HNSC	AZI2_S353 →	+0.981	+1.806	<.001	.002	3	1
HNSC	CAVIN4_S258 →	+1.364	+2.584	.002	<.001	3	1
HNSC	CIC_S1294 →	-0.838	-2.562	<.001	<.001	3	1
HNSC	DHRS11_S197 →	+0.974	+1.517	<.001	<.001	3	1
HNSC	FGD3_S101 →	+0.924	+0.996	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 368 associations by consensus.

UGT1A8 vs ATF7IP_S57 — HNSC

Explore this scatter interactively →