UGT1A7

Across TCGA patient cohorts, UGT1A7 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,635 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UGT1A7-associated proteins across cancer lineages are AKR1C2, AKR1C3, and SP110_S380. Each is linked with UGT1A7 in more than 4 cancer types. Because this analysis shows association rather than direction, both UGT1A7-to-partner and partner-to-UGT1A7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UGT1A7 versus AKR1C2 in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT1A7→partner) and Y-score (partner→UGT1A7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AKR1C2 →	+1.902	+2.540	<.001	<.001	3	5
LSCC	AKR1C3 →	+1.590	+2.521	<.001	<.001	3	5
LSCC	SP110_S380 →	-0.553	-1.579	<.001	<.001	3	4
PDAC	AKR1C3_S129 →	+1.814	+1.326	<.001	<.001	3	4
PDAC	MYO9B_S2141 →	-0.392	-0.935	<.001	<.001	3	3
PDAC	SPAST_S268 →	+1.393	+1.006	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,635 associations by consensus.

UGT1A7 vs AKR1C2 — LSCC

Explore this scatter interactively →