Across TCGA pan-cancer cohorts, UGT1A11P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of UGT1A11P’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where UGT1A11P RNA is repressed in tumor relative to normal tissue. In most cancer types UGT1A11P is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.
KIRP, KICH, and KIRC are the cancer types where UGT1A11P tumor–normal differential expression is most reproducible.