UGT1A11P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, UGT1A11P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of UGT1A11P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where UGT1A11P RNA is repressed in tumor relative to normal tissue. In most cancer types UGT1A11P is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and KIRC are the cancer types where UGT1A11P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UGT1A11P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
KIRPAllIII,IV−0.216<.0016view →
KICHMaleII,III,IV−0.152<.0016view →
KIRCMaleAll−0.141<.0013view →
STADMaleAll+0.035.0331view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration