UGT1A10

Across TCGA pan-cancer cohorts, UGT1A10 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated UGT1A10 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher UGT1A10 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated UGT1A10 expression acts as an unfavorable survival marker.

PDAC, LSCC, and COAD are the cancer types where UGT1A10 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	III,IV	0.195	0.620	.004	16	view →
LSCC	DFS	Tertile	All	0.542	1.000	.013	13	view →
COAD	DFS	Median	IV	0.493	0.944	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

UGT1A10–PDAC (DFS)

Open the PDAC breakdown →