UGT1A10

Across TCGA cell cohorts, UGT1A10 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UGT1A10-associated genes across cancer lineages are OR52E2, A3GALT2, and OR6B1. Each is linked with UGT1A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGT1A10-to-partner and partner-to-UGT1A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52E2 grouped by UGT1A10-low versus UGT1A10-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGT1A10→partner) and Y-score (partner→UGT1A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR52E2 →	+0.023	+5.169	<.001	.005	3	2
BLOOD_Lymphoma	A3GALT2 →	+0.038	+4.191	<.001	.007	3	1
BLOOD_Lymphoma	OR6B1 →	+0.009	+4.643	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

OR52E2 by UGT1A10 expression — BREAST

Explore this box plot interactively →