UGP2

Across TCGA patient cohorts, UGP2 mutation is significantly associated with the RNA expression of many other genes, with 4,131 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UGP2-associated genes across cancer lineages are ARF4P3, LRRC24, and SNORD3B-1. Each is linked with UGP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both UGP2-to-partner and partner-to-UGP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARF4P3 grouped by UGP2-low versus UGP2-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UGP2→partner) and Y-score (partner→UGP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ARF4P3 →	+0.084	+4.995	<.001	.009	3	2
LUSC	LRRC24 →	+0.090	+3.976	<.001	.003	3	2
UCEC	SNORD3B-1 →	+0.560	+1.499	<.001	.009	3	2
UCEC	EIF3JP1 →	+0.158	+1.751	<.001	.003	3	2
UCEC	EZH2P1 →	+0.269	+1.526	<.001	.002	3	2
BRCA	MIR6853 →	+0.242	+8.057	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,131 associations by consensus.

ARF4P3 by UGP2 expression — BRCA

Explore this box plot interactively →