UGDH-AS1

Across TCGA pan-cancer cohorts, UGDH-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated UGDH-AS1 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UGDH-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated UGDH-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and KIRC show a favorable association.

LUAD, KIRC, and UCS are the cancer types where UGDH-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.899	0.664	<.001	96	view →
KIRC	OS	Median	All	0.710	0.560	<.001	85	view →
UCS	DFS	Median	IV	0.952	0.367	.001	58	view →
KIRP	DFS	Median	IV	0.039	0.623	.001	36	view →
BRCA	OS	Tertile	III,IV	0.903	0.744	.003	29	view →
UVM	DFS	Tertile	III,IV	0.267	0.760	.016	20	view →
PRAD	DFS	Quartile	All	0.965	0.895	.001	18	view →
LIHC	DFS	Median	All	0.297	0.539	.001	15	view →
ACC	DFS	Quartile	All	0.611	0.835	.009	15	view →
HNSC	DFS	Quartile	IV	0.514	0.288	.008	14	view →
ESCA	OS	Tertile	All	0.625	0.454	.029	10	view →
SKCM	DFS	Quartile	All	0.698	0.549	.008	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

UGDH-AS1–LUAD (DFS)

Open the LUAD breakdown →