UFSP2

Across TCGA cell cohorts, UFSP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,763 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UFSP2-associated GO terms across cancer lineages are Ribosome disassembly, Cytoplasmic translational elongation, and Protein neddylation. Each is linked with UFSP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both UFSP2-to-partner and partner-to-UFSP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ribosome disassembly grouped by UFSP2-low versus UFSP2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UFSP2→partner) and Y-score (partner→UFSP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Ribosome disassembly →	+0.067	+0.645	<.001	<.001	3	13
SKIN	Cytoplasmic translational elongation →	+0.061	+0.467	<.001	.001	3	12
PANCREAS	Protein neddylation →	+0.086	+0.628	.001	<.001	3	11
BREAST	Rescue of stalled cytosolic ribosome →	+0.062	+0.560	.004	.006	2	12
BLOOD_Myeloma	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.053	+0.702	.001	.003	3	10
LIVER	DNA replication, synthesis of primer →	+0.148	+0.927	.001	.009	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,763 associations by consensus.

Ribosome disassembly by UFSP2 expression — PANCREAS

Explore this box plot interactively →