UFM1

Across TCGA patient cohorts, UFM1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,294 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UFM1-associated genes across cancer lineages are RSRC2, ALG5, and TPT1. Each is linked with UFM1 in more than 4 cancer types. Because this analysis shows association rather than direction, both UFM1-to-partner and partner-to-UFM1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UFM1 versus RSRC2 in LSCC, with a Pearson correlation of -0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UFM1→partner) and Y-score (partner→UFM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RSRC2 →	-0.530	-0.327	<.001	<.001	3	5
OV	ALG5 →	+0.646	+0.348	<.001	<.001	3	5
UCEC	TPT1 →	+0.496	+0.289	.001	.001	3	5
LSCC	RFC5 →	-0.702	-0.225	<.001	<.001	3	4
LSCC	NAP1L1 →	-0.604	-0.293	<.001	<.001	3	4
LSCC	YTHDF2 →	-0.472	-0.332	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,294 associations by consensus.

UFM1 vs RSRC2 — LSCC

Explore this scatter interactively →