UFL1

Across TCGA patient cohorts, UFL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,160 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible UFL1-associated GO terms across cancer lineages are Prenylation, Ribosome-associated ubiquitin-dependent protein catabolic process, and Protein polyufmylation. Each is linked with UFL1 in more than 33 cancer types. Because this analysis shows association rather than direction, both UFL1-to-partner and partner-to-UFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Prenylation grouped by UFL1-low versus UFL1-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UFL1→partner) and Y-score (partner→UFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Prenylation →	+0.086	+1.734	<.001	<.001	3	34
THYM	Ribosome-associated ubiquitin-dependent protein catabolic process →	+0.108	+1.334	<.001	<.001	3	34
SCLC	Protein polyufmylation →	+0.124	+0.546	<.001	<.001	3	34
UVM	Vesicle tethering →	+0.082	+1.790	<.001	<.001	3	33
SCLC	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.115	+0.598	.003	<.001	3	33
CHOL	Regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay →	+0.076	+1.253	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,160 associations by consensus.

Prenylation by UFL1 expression — UVM

Explore this box plot interactively →