UFL1

Across TCGA patient cohorts, UFL1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,724 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UFL1-associated genes across cancer lineages are PPP2R1A, PPP5C, and CD164. Each is linked with UFL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both UFL1-to-partner and partner-to-UFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UFL1 versus PPP2R1A in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UFL1→partner) and Y-score (partner→UFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	PPP2R1A →	-0.720	-0.304	<.001	.001	3	5
OV	PPP5C →	-0.683	-0.281	.001	<.001	3	5
BRCA	CD164 →	+0.647	+0.209	.005	<.001	3	5
HNSC	SAE1 →	-0.756	-0.194	<.001	<.001	3	5
HNSC	C19orf48 →	-1.017	-0.192	<.001	<.001	3	5
HNSC	MANEA →	+0.666	+0.264	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,724 associations by consensus.

UFL1 vs PPP2R1A — OV

Explore this scatter interactively →