UFL1

Across TCGA patient cohorts, UFL1 mutation is significantly associated with the RNA expression of many other genes, with 2,453 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UFL1-associated genes across cancer lineages are SNRPGP17, RNA5SP411, and FAM230H. Each is linked with UFL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UFL1-to-partner and partner-to-UFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP17 grouped by UFL1-low versus UFL1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UFL1→partner) and Y-score (partner→UFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPGP17 →	+0.239	+2.071	<.001	<.001	3	2
UCEC	RNA5SP411 →	+0.743	+1.808	.001	<.001	3	2
HNSC	FAM230H →	+0.007	+4.548	<.001	.001	3	2
SKCM	MLLT10P2 →	+0.136	+4.884	<.001	.004	3	2
PRAD	NCOR1P2 →	+0.142	+5.008	<.001	.003	3	2
UCEC	SNX3P1Y →	+0.058	+3.671	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,453 associations by consensus.

SNRPGP17 by UFL1 expression — UCEC

Explore this box plot interactively →