UFL1

Across TCGA cell cohorts, UFL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,037 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible UFL1-associated GO terms across cancer lineages are Protein polyufmylation, Protein K69-linked ufmylation, and Golgi organization. Each is linked with UFL1 in more than 16 cancer types. Because this analysis shows association rather than direction, both UFL1-to-partner and partner-to-UFL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyufmylation grouped by UFL1-low versus UFL1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UFL1→partner) and Y-score (partner→UFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein polyufmylation →	+0.168	+0.777	<.001	<.001	3	17
BLOOD_Myeloma	Protein K69-linked ufmylation →	+0.168	+0.777	<.001	<.001	3	17
BLOOD_Lymphoma	Golgi organization →	+0.067	+1.164	<.001	<.001	3	16
BREAST	Cytoplasmic translational elongation →	+0.065	+0.558	<.001	<.001	3	15
BREAST	Rescue of stalled cytosolic ribosome →	+0.075	+0.459	<.001	<.001	3	14
SKIN	7-methylguanosine RNA capping →	+0.114	+0.844	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,037 associations by consensus.

Protein polyufmylation by UFL1 expression — BLOOD_Myeloma

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