UFL1-AS1

Across TCGA pan-cancer cohorts, UFL1-AS1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated UFL1-AS1 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher UFL1-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated UFL1-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and LGG show a favorable association.

UCS, LGG, and KIRP are the cancer types where UFL1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.865	0.479	<.001	78	view →
LGG	DFS	Median	All	0.810	0.661	<.001	47	view →
KIRP	OS	Tertile	All	0.948	0.521	.003	46	view →
SKCM	OS	Median	II,III,IV	0.215	0.428	.011	40	view →
KIRC	DFS	Quartile	IV	0.451	0.766	.017	22	view →
DLBC	DFS	Quartile	III,IV	0.074	0.984	.008	21	view →
STAD	OS	Tertile	III,IV	0.521	0.294	.028	14	view →
GBM	DFS	Median	All	0.246	0.155	.005	13	view →
LUSC	DFS	Quartile	All	0.646	0.888	.003	13	view →
SARC	DFS	Tertile	All	0.507	0.301	.014	13	view →
BLCA	DFS	Median	IV	0.371	0.556	.003	12	view →
UVM	OS	Median	All	0.482	0.720	.041	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

UFL1-AS1–UCS (OS)

Open the UCS breakdown →