UFD1

Across TCGA patient cohorts, UFD1 protein abundance is significantly associated with the RNA expression of many other genes, with 8,869 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UFD1-associated genes across cancer lineages are NPLOC4, MRPS7, and ANAPC11. Each is linked with UFD1 in more than 6 cancer types. Because this analysis shows association rather than direction, both UFD1-to-partner and partner-to-UFD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UFD1 versus NPLOC4 in LUAD, with a Pearson correlation of 0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UFD1→partner) and Y-score (partner→UFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NPLOC4 →	+0.532	+0.183	<.001	<.001	3	7
OV	MRPS7 →	+0.462	+0.148	<.001	.003	3	5
OV	ANAPC11 →	+0.759	+0.257	<.001	<.001	3	5
OV	SAP30BP →	+0.347	+0.221	<.001	<.001	3	5
LSCC	PSMD12 →	+0.738	+0.281	<.001	<.001	3	5
OV	OXLD1 →	+0.714	+0.195	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,869 associations by consensus.

UFD1 vs NPLOC4 — LUAD

Explore this scatter interactively →