UFD1

Across TCGA cell cohorts, UFD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,645 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UFD1-associated GO terms across cancer lineages are Interleukin-34-mediated signaling pathway, Symbiont-mediated disruption of host cellular anatomical structure, and Symbiont-mediated disruption of host anatomical structure. Each is linked with UFD1 in more than 12 cancer types. Because this analysis shows association rather than direction, both UFD1-to-partner and partner-to-UFD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Interleukin-34-mediated signaling pathway grouped by UFD1-low versus UFD1-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UFD1→partner) and Y-score (partner→UFD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Interleukin-34-mediated signaling pathway →	+0.200	+0.980	<.001	.004	3	13
BREAST	Symbiont-mediated disruption of host cellular anatomical structure →	+0.149	+0.795	.001	.002	3	13
BREAST	Symbiont-mediated disruption of host anatomical structure →	+0.149	+0.795	.001	.002	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome separation →	+0.132	+0.877	.001	<.001	3	13
PANCREAS	Mitotic spindle elongation →	+0.218	+0.626	<.001	.001	3	13
PANCREAS	Mitotic spindle midzone assembly →	+0.218	+0.626	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,645 associations by consensus.

Interleukin-34-mediated signaling pathway by UFD1 expression — URINARY_TRACT

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