UCP2

Across TCGA patient cohorts, UCP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,190 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible UCP2-associated proteins across cancer lineages are SAMHD1, IKZF1, and IL16. Each is linked with UCP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both UCP2-to-partner and partner-to-UCP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCP2 versus SAMHD1 in HNSC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UCP2→partner) and Y-score (partner→UCP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	+0.497	+0.727	<.001	<.001	3	6
HNSC	IKZF1 →	+0.649	+1.000	<.001	.001	3	6
HNSC	IL16 →	+0.802	+1.322	<.001	<.001	3	6
HNSC	BTK →	+0.527	+0.751	<.001	<.001	3	6
GBM	DOCK11 →	+0.304	+0.685	<.001	<.001	3	6
HNSC	DOCK2 →	+0.518	+0.839	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,190 associations by consensus.

UCP2 vs SAMHD1 — HNSC

Explore this scatter interactively →