UCN2

Across TCGA cell cohorts, UCN2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,577 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UCN2-associated GO terms across cancer lineages are Endodermal cell differentiation, Collagen fibril organization, and Pyrimidine-containing compound transmembrane transport. Each is linked with UCN2 in more than 14 cancer types. Because this analysis shows association rather than direction, both UCN2-to-partner and partner-to-UCN2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endodermal cell differentiation grouped by UCN2-low versus UCN2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCN2→partner) and Y-score (partner→UCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Endodermal cell differentiation →	+0.144	+1.480	.005	.001	3	15
BONE	Collagen fibril organization →	+0.384	+2.106	<.001	<.001	3	14
STOMACH	Pyrimidine-containing compound transmembrane transport →	-0.207	-1.663	<.001	.001	3	13
BONE	Dentinogenesis →	+1.836	+1.340	<.001	<.001	3	12
SOFT_TISSUE	Endoderm formation →	+0.155	+1.513	<.001	<.001	3	12
BONE	Positive regulation of focal adhesion assembly →	+0.212	+1.861	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,577 associations by consensus.

Endodermal cell differentiation by UCN2 expression — BONE

Explore this box plot interactively →