UCN

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, UCN RNA expression is significantly associated with the go_rna of many other GO terms, with 2,318 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UCN-associated GO terms across cancer lineages are Detection of chemical stimulus involved in sensory perception of pain, Protein polyglycylation, and Positive regulation of cAMP/PKA signal transduction. Each is linked with UCN in more than 12 cancer types. Because this analysis shows association rather than direction, both UCN-to-partner and partner-to-UCN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Detection of chemical stimulus involved in sensory perception of pain grouped by UCN-low versus UCN-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCN→partner) and Y-score (partner→UCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STOMACHDetection of chemical stimulus involved in sensory perception of pain →+0.941+0.451<.001<.001313
LUNG_NSCLC_LUSCProtein polyglycylation →+1.429+0.651.002.009112
LIVERPositive regulation of cAMP/PKA signal transduction →-0.209-0.532.002.004210
SOFT_TISSUECalcium-independent cell-matrix adhesion →+0.142+0.345<.001<.00139
OESOPHAGUSCilium-dependent cell motility →-0.100-0.660.004.005210
OESOPHAGUSCilium or flagellum-dependent cell motility →-0.100-0.660.004.005210
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,318 associations by consensus.

Detection of chemical stimulus involved in sensory perception of pain by UCN expression — STOMACH

Box plot of Detection of chemical stimulus involved in sensory perception of pain in UCN-low vs UCN-high samples in STOMACH.

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Exploration