Across TCGA patient cohorts, UCKL1 mutation is significantly associated with the total protein of many other genes, with 56 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UCKL1-associated genes across cancer lineages are PDCD4, EGFR_pY1068, and ATM. Each is linked with UCKL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both UCKL1-to-partner and partner-to-UCKL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCKL1→partner) and Y-score (partner→UCKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.441	-2.321	.009	.033	3	3
UCEC	EGFR_pY1068 →	-0.257	-1.925	.004	.005	3	2
UCEC	ATM →	-0.489	-1.925	.002	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.884	+2.700	<.001	.005	3	2
COAD	GATA6 →	-0.303	-3.000	.003	.036	3	2
COAD	Tuberin →	-0.388	-3.161	.014	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 56 associations by consensus.

Exploration

UCKL1 survival (RNA) · tumor vs normal (RNA) · all UCKL1 data types