Across TCGA cell cohorts, UCKL1 mutation is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UCKL1-associated genes across cancer lineages are OR11H1, DMRTC1B, and MC2R. Each is linked with UCKL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UCKL1-to-partner and partner-to-UCKL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCKL1→partner) and Y-score (partner→UCKL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OR11H1 →	+0.040	+4.882	<.001	<.001	3	2
SKIN	DMRTC1B →	+0.076	+3.930	<.001	.003	3	1
SKIN	MC2R →	+0.028	+4.510	<.001	.001	3	1
SKIN	SNTN →	+0.038	+4.196	.001	.002	3	1
SKIN	PRAMEF17 →	+0.010	+4.437	<.001	.004	3	1
BLOOD_Leukemia	TBPL2 →	+0.113	+4.044	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

UCKL1 survival (RNA) · tumor vs normal (RNA) · all UCKL1 data types