UCKL1-AS1

Across TCGA pan-cancer cohorts, UCKL1-AS1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of UCKL1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where UCKL1-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types UCKL1-AS1 is over-expressed in tumor, although a few such as THCA and LUAD show the opposite, repressed pattern.

KICH, COAD, and THCA are the cancer types where UCKL1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in UCKL1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	+1.177	<.001	11	view →
COAD	All	IV	+0.921	<.001	11	view →
THCA	Female	II,III,IV	−0.530	<.001	11	view →
LUAD	All	All	−0.609	<.001	7	view →
KIRC	All	All	+0.135	<.001	7	view →
BRCA	All	II,III,IV	+0.219	.002	6	view →
LIHC	Female	All	+0.169	<.001	6	view →
READ	All	All	+0.605	<.001	3	view →
LUSC	All	All	−0.452	.005	3	view →
CHOL	All	All	+0.948	<.001	2	view →
KIRP	All	IV	+0.260	.033	2	view →
PRAD	All	All	+0.171	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

UCKL1-AS1–KICH

Open the KICH breakdown →