UCK2

Across TCGA patient cohorts, UCK2 protein abundance is significantly associated with the RNA expression of many other genes, with 17,539 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible UCK2-associated genes across cancer lineages are BUB1, CHRNA5, and ARHGAP11A. Each is linked with UCK2 in more than 6 cancer types. Because this analysis shows association rather than direction, both UCK2-to-partner and partner-to-UCK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCK2 versus BUB1 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCK2→partner) and Y-score (partner→UCK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BUB1 →	+0.968	+0.290	<.001	.001	3	7
LSCC	CHRNA5 →	+0.841	+0.436	<.001	<.001	3	7
GBM	ARHGAP11A →	+0.880	+0.282	<.001	.001	3	7
HNSC	ASPM →	+1.136	+0.451	<.001	<.001	3	7
LUAD	GINS1 →	+0.951	+0.461	<.001	<.001	3	6
GBM	MYBL2 →	+1.187	+0.275	.002	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,539 associations by consensus.

UCK2 vs BUB1 — GBM

Explore this scatter interactively →