UCK1

Across TCGA cell cohorts, UCK1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible UCK1-associated genes across cancer lineages are REG3G, KRTAP4-1, and OR10K2. Each is linked with UCK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UCK1-to-partner and partner-to-UCK1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, REG3G grouped by UCK1-low versus UCK1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCK1→partner) and Y-score (partner→UCK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	REG3G →	+0.033	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP4-1 →	+0.092	+4.867	.003	.009	3	1
BREAST	OR10K2 →	+0.063	+5.781	<.001	.001	3	1
BREAST	PABPC1L2A →	+0.083	+5.169	<.001	.005	3	1
BREAST	OR10T2 →	+0.183	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

REG3G by UCK1 expression — BLOOD_Lymphoma

Explore this box plot interactively →