UCHL5

Across TCGA cell cohorts, UCHL5 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,201 significant associations in total. BONE shows the largest number of these associations.

The most reproducible UCHL5-associated GO terms across cancer lineages are Nuclear pore organization, DNA replication initiation, and Protein localization to nuclear inner membrane. Each is linked with UCHL5 in more than 18 cancer types. Because this analysis shows association rather than direction, both UCHL5-to-partner and partner-to-UCHL5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore organization grouped by UCHL5-low versus UCHL5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL5→partner) and Y-score (partner→UCHL5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nuclear pore organization →	+0.185	+0.896	<.001	<.001	3	19
BONE	DNA replication initiation →	+0.191	+0.917	<.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Protein localization to nuclear inner membrane →	+0.195	+0.944	.001	.002	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear pore complex assembly →	+0.139	+0.861	.005	.005	3	16
OVARY	DNA-templated DNA replication →	+0.100	+0.947	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair →	+0.075	+0.708	<.001	.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,201 associations by consensus.

Nuclear pore organization by UCHL5 expression — BONE

Explore this box plot interactively →