UCHL3

Across TCGA patient cohorts, UCHL3 protein abundance is significantly associated with the RNA expression of many other genes, with 8,993 significant associations in total. COAD shows the largest number of these associations.

The most reproducible UCHL3-associated genes across cancer lineages are COMMD6, ALG5, and TM9SF2. Each is linked with UCHL3 in more than 5 cancer types. Because this analysis shows association rather than direction, both UCHL3-to-partner and partner-to-UCHL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCHL3 versus COMMD6 in BRCA, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL3→partner) and Y-score (partner→UCHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	COMMD6 →	+0.658	+0.385	<.001	<.001	3	6
LUAD	ALG5 →	+0.389	+0.219	<.001	<.001	3	5
BRCA	TM9SF2 →	+0.531	+0.383	<.001	<.001	3	5
BRCA	COG6 →	+0.551	+0.312	<.001	<.001	3	5
BRCA	COG3 →	+0.473	+0.330	<.001	<.001	3	5
LSCC	GTF2F2 →	+0.458	+0.302	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,993 associations by consensus.

UCHL3 vs COMMD6 — BRCA

Explore this scatter interactively →