UCHL3

Across TCGA cell cohorts, UCHL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,978 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UCHL3-associated GO terms across cancer lineages are Protein localization to chromosome, centromeric region, Positive regulation of translational initiation in response to stress, and Protein localization to kinetochore. Each is linked with UCHL3 in more than 11 cancer types. Because this analysis shows association rather than direction, both UCHL3-to-partner and partner-to-UCHL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to chromosome, centromeric region grouped by UCHL3-low versus UCHL3-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL3→partner) and Y-score (partner→UCHL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein localization to chromosome, centromeric region →	+0.143	+1.002	<.001	<.001	3	12
BONE	Positive regulation of translational initiation in response to stress →	+0.197	+1.432	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.163	+1.188	<.001	<.001	3	11
LUNG_SCLC	Mitochondrial translational termination →	+0.136	+0.915	<.001	.005	2	11
OVARY	Response to X-ray →	+0.062	+0.563	<.001	.002	3	10
LUNG_NSCLC_LUSC	Protein polyglycylation →	-1.539	-1.171	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,978 associations by consensus.

Protein localization to chromosome, centromeric region by UCHL3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →