UCHL1

Across TCGA patient cohorts, UCHL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,366 significant associations in total. GBM shows the largest number of these associations.

The most reproducible UCHL1-associated proteins across cancer lineages are BAG2, PFN2, and MAP1A. Each is linked with UCHL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both UCHL1-to-partner and partner-to-UCHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UCHL1 versus BAG2 in CCRCC, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL1→partner) and Y-score (partner→UCHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	BAG2 →	+0.667	+2.072	<.001	<.001	3	8
LUAD	PFN2 →	+0.682	+2.317	<.001	<.001	3	7
GBM	MAP1A →	+0.624	+1.318	<.001	<.001	3	7
UCEC	TPX2 →	+0.961	+2.297	<.001	<.001	3	6
BRCA	MTMR2 →	+0.279	+1.369	.006	.003	3	6
OV	PLOD1 →	+0.677	+2.359	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,366 associations by consensus.

UCHL1 vs BAG2 — CCRCC

Explore this scatter interactively →