UCHL1

Across TCGA cell cohorts, UCHL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,548 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible UCHL1-associated GO terms across cancer lineages are DNA-templated transcription initiation, Transcription initiation at RNA polymerase II promoter, and RNA catabolic process. Each is linked with UCHL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both UCHL1-to-partner and partner-to-UCHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated transcription initiation grouped by UCHL1-low versus UCHL1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL1→partner) and Y-score (partner→UCHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA-templated transcription initiation →	+0.068	+4.740	.006	.008	1	12
BREAST	Transcription initiation at RNA polymerase II promoter →	+0.055	+3.435	.005	.002	3	10
PANCREAS	RNA catabolic process →	+0.056	+1.772	<.001	<.001	3	10
PANCREAS	Translational initiation →	+0.100	+2.112	<.001	<.001	3	10
PANCREAS	RNA splicing, via transesterification reactions →	+0.061	+1.542	<.001	.003	3	10
PANCREAS	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile →	+0.061	+1.542	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,548 associations by consensus.

DNA-templated transcription initiation by UCHL1 expression — OESOPHAGUS

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