UCHL1

Across TCGA cell cohorts, UCHL1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UCHL1-associated genes across cancer lineages are GPR171. Each is linked with UCHL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both UCHL1-to-partner and partner-to-UCHL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPR171 grouped by UCHL1-low versus UCHL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UCHL1→partner) and Y-score (partner→UCHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GPR171 →	+0.027	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GPR171 by UCHL1 expression — LARGE_INTESTINE

Explore this box plot interactively →