UBXN8

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBXN8 protein abundance is significantly associated with the RNA expression of many other genes, with 1,492 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible UBXN8-associated genes across cancer lineages are TNFSF10, GLOD5, and APH1A. Each is linked with UBXN8 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN8-to-partner and partner-to-UBXN8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, UBXN8 versus TNFSF10 in CCRCC, with a Pearson correlation of -0.81.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN8→partner) and Y-score (partner→UBXN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCTNFSF10 →-1.272-0.754.002<.00132
CCRCCGLOD5 →-1.334-0.576.002.00132
CCRCCAPH1A →-0.397-0.770<.001.00132
CCRCCCALM3 →-0.576-0.641.001<.00132
HNSCHCAR2 →+2.287+0.812.003.00632
BRCAMETTL23 →-0.724-0.667.005.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,492 associations by consensus.

UBXN8 vs TNFSF10 — CCRCC

Per-sample scatter of UBXN8 vs TNFSF10 in CCRCC (Pearson r = -0.81).

Explore this scatter interactively →

Exploration