UBXN8

Across TCGA patient cohorts, UBXN8 mutation is significantly associated with the RNA expression of many other genes, with 1,852 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN8-associated genes across cancer lineages are RNA5SP424, RNA5SP146, and RPS3AP17. Each is linked with UBXN8 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN8-to-partner and partner-to-UBXN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP424 grouped by UBXN8-low versus UBXN8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN8→partner) and Y-score (partner→UBXN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP424 →	+0.200	+2.657	.002	.006	3	2
UCEC	RNA5SP146 →	+0.232	+2.387	.001	.005	3	2
UCEC	RPS3AP17 →	+0.071	+2.539	.006	.003	3	2
COAD	CDY3P →	+0.089	+7.741	<.001	.009	3	2
BRCA	MIR548AP →	+0.322	+8.055	<.001	.007	3	1
UCEC	GOLGA6L10 →	+0.220	+3.425	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,852 associations by consensus.

RNA5SP424 by UBXN8 expression — UCEC

Explore this box plot interactively →