UBXN8

Across TCGA cell cohorts, UBXN8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,499 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible UBXN8-associated GO terms across cancer lineages are Mismatch repair, RNA polymerase II transcription initiation surveillance, and Methylation. Each is linked with UBXN8 in more than 10 cancer types. Because this analysis shows association rather than direction, both UBXN8-to-partner and partner-to-UBXN8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mismatch repair grouped by UBXN8-low versus UBXN8-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN8→partner) and Y-score (partner→UBXN8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Mismatch repair →	+0.081	+1.112	.002	.002	3	11
BONE	RNA polymerase II transcription initiation surveillance →	+0.099	+1.006	<.001	.001	3	10
UPPER_AERODIGESTIVE_TRACT	Methylation →	+0.056	+1.010	.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Mitochondrial RNA metabolic process →	+0.080	+0.779	.001	.003	3	9
CNS	snRNA processing →	+0.065	+0.737	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Maturation of LSU-rRNA →	+0.080	+0.913	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,499 associations by consensus.

Mismatch repair by UBXN8 expression — LIVER

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