UBXN7

Across TCGA pan-cancer cohorts, UBXN7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated UBXN7 data layer compared with 27 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher UBXN7 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated UBXN7 expression acts as an unfavorable survival marker, although some lineages such as LUAD and GBM show a favorable association.

LUAD, GBM, and UCEC are the cancer types where UBXN7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	All	0.920	0.701	.010	11	view →
GBM	OS	Quartile	All	0.567	0.259	.003	8	view →
UCEC	OS	Quartile	All	0.884	1.000	.026	8	view →
HNSC	OS	Quartile	All	0.587	0.886	.009	5	view →
CCRCC	DFS	Tertile	III,IV	1.000	0.042	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

UBXN7–LUAD (OS)

Open the LUAD breakdown →