UBXN7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, UBXN7 mutation is significantly associated with the RNA expression of many other genes, with 4,402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN7-associated genes across cancer lineages are RNA5SP461, RNU5E-9P, and RN7SKP265. Each is linked with UBXN7 in more than 2 cancer types. Because this analysis shows association rather than direction, both UBXN7-to-partner and partner-to-UBXN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP461 grouped by UBXN7-low versus UBXN7-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN7→partner) and Y-score (partner→UBXN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRNA5SP461 →+0.247+7.954<.001.00833
CESCRNU5E-9P →+0.223+4.569<.001.00533
COADRN7SKP265 →+0.325+6.409<.001<.00133
UCECCENPU →+0.685+1.979<.001<.00132
UCECBDH1 →+0.403+1.711.004.00132
UCECEN2 →+1.081+4.129<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

RNA5SP461 by UBXN7 expression — HNSC

Box plot of RNA5SP461 in UBXN7-low vs UBXN7-high samples in HNSC.

Explore this box plot interactively →

Exploration