UBXN7

Across TCGA cell cohorts, UBXN7 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBXN7-associated genes across cancer lineages are OR52H1, PRSS54, and TTLL8. Each is linked with UBXN7 in more than 1 cancer types. Because this analysis shows association rather than direction, both UBXN7-to-partner and partner-to-UBXN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52H1 grouped by UBXN7-low versus UBXN7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN7→partner) and Y-score (partner→UBXN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR52H1 →	+0.038	+4.669	<.001	<.001	3	2
LARGE_INTESTINE	PRSS54 →	+0.035	+3.345	<.001	.007	3	1
LARGE_INTESTINE	TTLL8 →	+0.003	+4.022	<.001	.006	3	1
LARGE_INTESTINE	SLC22A8 →	+0.023	+3.196	.002	.007	3	1
LARGE_INTESTINE	TBC1D21 →	+0.010	+4.022	<.001	.006	3	1
LARGE_INTESTINE	REG1B →	+1.756	+3.196	.007	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

OR52H1 by UBXN7 expression — LARGE_INTESTINE

Explore this box plot interactively →