UBXN7

Across TCGA cell cohorts, UBXN7 mutation is significantly associated with the mutation status of many other genes, with 2,423 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible UBXN7-associated genes across cancer lineages are TBC1D9B, RNF145, and PRRC2B. Each is linked with UBXN7 in more than 3 cancer types. Because this analysis shows association rather than direction, both UBXN7-to-partner and partner-to-UBXN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D9B grouped by UBXN7-low versus UBXN7-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN7→partner) and Y-score (partner→UBXN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	TBC1D9B →	+4.392	+4.954	.008	.008	1	4
UPPER_AERODIGESTIVE_TRACT	RNF145 →	+5.392	+5.392	.004	.004	1	4
BLOOD_Lymphoma	PRRC2B →	+3.554	+3.731	.003	.003	1	4
BLOOD_Lymphoma	CACNG2 →	+4.969	+4.014	.008	.008	1	3
UPPER_AERODIGESTIVE_TRACT	MBD6 →	+5.392	+5.392	.004	.004	1	3
BLOOD_Lymphoma	VWCE →	+3.554	+3.731	.003	.003	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,423 associations by consensus.

TBC1D9B by UBXN7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →