UBXN6

Across TCGA patient cohorts, UBXN6 RNA expression is significantly associated with the mutation status of many other genes, with 9,865 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible UBXN6-associated genes across cancer lineages are FNDC1, DOCK2, and FAM135B. Each is linked with UBXN6 in more than 4 cancer types. Because this analysis shows association rather than direction, both UBXN6-to-partner and partner-to-UBXN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FNDC1 grouped by UBXN6-low versus UBXN6-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (UBXN6→partner) and Y-score (partner→UBXN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FNDC1 →	+1.214	+0.269	<.001	<.001	3	5
UCEC	DOCK2 →	+1.375	+0.333	<.001	<.001	3	4
UCEC	FAM135B →	+1.305	+0.307	<.001	<.001	3	4
UCEC	OLFM3 →	+2.507	+0.360	<.001	<.001	3	3
SKCM	GNAZ →	+3.813	+0.396	<.001	.005	3	3
SKCM	KIT →	+3.347	+0.356	.004	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,865 associations by consensus.

FNDC1 by UBXN6 expression — UCEC

Explore this box plot interactively →